LOCATION: Indianapolis, IN

The Aseptic Process Engineer- Syringe Filling provides technical leadership and high-level engineering expertise for all syringe filling and inspection operations in the Parenteral Plant.

KEY OBJECTIVES/DELIVERABLES:

Coach and mentor engineering associates in aspects of syringe filling and handling, including: process knowledge, problem solving, project management, and engineering design.  Provide companywide syringe process expertise.  Identify syringe process knowledge gaps that impact equipment and process capability.  Review and track key syringe filling line process metrics.  Improve throughput and optimize the syringe filling
line(s)

MINIMUM REQUIREMENTS: Bachelor’s Degree in Engineering or related field.  Minimum of 10 years syringe filling experience (Design or operations of syringe filling / processing equipment).   Qualified candidates must be legally authorized to be
employed in the United States. Lilly does not anticipate providing sponsorship
for employment visa status (e.g., H-1B or TN status) for this employment
position.

ADDITIONAL SKILLS/PREFERENCES: Technology Glass handling and/ or glass fractographical experience.

OTHER CONSIDERATIONS:  Day Shift, possible after-hour support.

Project Delivery and/or Plant Shutdown may coincide with
company holidays.

Occasional travel may be required for training,
conferences, capital projects, and support additional syringe filling sites.

Chemicals Manufacturing

Location:  Indianapolis, Indiana

Ideal Candidate:

5+ to 7 years of experience
Management Experience Required – No
Minimum Education – Bachelor’s Degree
Willingness to Travel – Occasionally

The Chemical Engineer is responsible for preliminary and final process design work for new chemical manufacturing facilities and improvements to existing facilities. This includes performing detailed design calculations, identifying opportunities for process optimization, recommending process design changes, and assisting with the implementation and start-up of those recommendations. Some travel to our manufacturing sites will be required. 

Duties and Responsibilities:

    * Develop preliminary scope and plan for new projects, estimate preliminary project costs and    benefits.

    * Prepare new, or modify existing plant Process Flow Diagrams (PFD’s).

    * Complete detailed Material and Energy Balances for new or modified processes.

    * Prepare new or modified Process and Instrumentation Diagrams (P&ID’s).

    * Size and specify new process equipment and re-rate existing equipment for new capacities or services.

    * Size and specify Safety Relief Devices and vent systems.

    * Prepare new, or modify existing Plant Operating Procedures to accurately reflect project scope,

      control philosophy, and objectives.

    * Work with plant operating personnel to troubleshoot plant operation issues, especially when associated with project implementations.

    * Work on Continuous Improvement Projects as identified or needed. Areas of emphasis include:

      manufacturing cost reduction, capacity improvements/cycle time reductions, energy and waste

      reduction, and process reliability.

Education and Experience Requirements:

    * Minimum of a Bachelors Degree in Chemical Engineering.

    * 5 – 10 years experience in process design or process engineering.

    * Fundamental knowledge of continuous and batch chemical operations including reaction,

      distillation, heat exchange, solids handling, utilities and process control.

    * Problem solving skills including the ability to analyze technical data and make creative and

      balanced decisions.

    * Strong written and verbal communication skills.

    * Self motivated with the ability to take initiative and work successfully in cross functional teams.

    * Flexibility to work in both office and operating plant environments on a wide variety of activities.

    * Working Knowledge of process safety tools (PHA, LOPA, MOC, Root Cause Analysis, etc.).

Preferred Skills and Competencies:

    * Process simulation experience (Aspen Plus and/or PD-Plus, hydraulic modeling software).

    * Familiarity with Six Sigma processes.

    * Prior experience conducting process plant optimization

Location:  Indianapolis, IN

Ideal Candidate: 

2+ to 5 years of experience
Management Experience Required – No
Education – BS or MS (This is not a PhD position)
Willingness to Travel – Occasionally

This cross functional position is an integral part of the Protein Optimization Characterization lab within the Protein Optimization Team of Biotechnology Discovery Research, which is responsible for generating, characterizing, and optimizing biotherapeutics from lead generation to lead optimization and preclinical development. We are seeking a motivated research associate with a BS or MS degree in biochemistry or related field that exhibits a broad analytical aptitude who can function in a highly collaborative environment performing analytical purification and biochemical characterization of proteins/peptides in a multidisciplinary team focusing on optimizing therapeutic properties of biotherapeutics.

KEY OBJECTIVES/DELIVERABLES:

The individual will perform mass spectrometry of proteins and peptides to support multiple drug discovery programs.

Additionally, they will perform appropriate protein sample preparation methods (e.g. in gel digestion, in solution digestion, protein/peptide separation on HPLC, etc.).

The individual will be responsible performing intact mass analysis, peptide mapping and LC MS/MS analysis.

Additionally the successful candidate will operate, maintain and troubleshoot liquid chromatography, mass spectrometers and auxiliary instrumentation.

The individual will also employ scientific background and communication skills to professionally support investigators by recommending sample preparation methods, advising in experimental design, and assisting in the analysis, evaluation, and interpretation of experimental results in conjunction with other staff within the Protein Optimization Team.

MINIMUM REQUIREMENTS:

A BS with more than two years of research experience or MS degree in protein biochemistry or related field is required.

This position requires knowledge and experience of HPLC, LC-MS, and LC MS/MS-based protein analysis and hands-on experience with purification and characterization of proteins

Characterize proteins by performing intact mass analysis, peptide mapping and LC MS/MS

Analytical biochemistry technique experience

Location:  Indianapolis, IN

The Ideal Candidate:

5+ to 7 years of experience

Management Experience Required – Yes

Minimum Education –Master’s Degree

 Willingness to Travel – Occasionally

The Clinical Trial Support Operations (CTSO) team is responsible for providing clinical trial study drug management services and supporting the Demand Management side of the business by providing the following support services:  Distribution, Study Order Management and Ownership, and Business Systems Support & Operations. The Clinical Trial Support Operations team partners with appropriate business partners to ensure study order ownership and support to successfully enable clinical research.

The Director is responsible for developing and implementing the strategy for the Clinical Trial Support Operations department, effectively managing the capacity and capabilities of the organization, ensuring strong cross functional partnerships exist in support of the portfolio, and overseeing compliant business processes and deliverables that lead to the on time delivery of Investigational Products that enable Clinical Research.  The Director provides appropriate oversight to ensure full compliance with GxP, corporate standards/policies/procedures, operational excellence, continuous improvement, personnel development and overall leadership.

KEY OBJECTIVES/DELIVERABLES:

Execute all position responsibilities in a way that integrates ethics and compliance and follows all applicable regulations, the Corporate Integrity Agreement, The Red Book, and policies related to job content.

Management

• Accountable for the global business operation process and execution of the CTSO group
• Provide leadership, direction and oversight for -50 people in Indianapolis, Indiana and Brussels, Belgium
• Organize the department so as to reach the fixed objectives.  Recruit the necessary employees and ensure their training.  Foster the development of technical and organizational expertise.  Forecast adequate budgets and manage the department accordingly.
• Ensure that CT material is produced and supplied on time and in compliance with the quality standards and regulatory requirements (FDA, EMEA, ICH)
• Ensure the appropriate facilities, buildings and equipment are available
• Develop effective relationships with the customers and business partners
• Accountable for delivery of information and services to support the global clinical development strategy.
• Drive continuous process improvement and increased efficiency
• Accountable for all aspects quality and compliance
• Effectively manage all communication channels
• Anticipate and resolve issues with the organization and key stake-holders
• Accountable for operational leadership and excellence
• Accountable for development and communication of objectives as well as execution against the objectives
• Accountable for ensuring development of operations skills and capabilities.
• Accountable for implementation and utilization of all supply chain management principles and practices.
• Strategy
• Develop the Vision and associated strategy and plans to successfully deliver all CTSO responsibilities
• Responsible for contributing to and leading the organization to deliver the CTMS vision and strategy.
• Foster and support continuous process improvements
• Support all aspects of the CTMS transformation agenda

External Focus

• Maintain and foster contacts with the other global functions in Indianapolis and ELECTS (CTMM, outsourcing, packaging, quality, manufacturing, etc.)
• Create relationships with customers and external organizations or other pharmaceutical companies (benchmarking).
• Leverage the academic environment to foster innovation.
• Promote the participation of employees in external activities, congresses, seminars that will allow them to exchange professional information.
• Actively manages relationships with external business partners to ensure a positive and productive working environment and enable a FIPNET working environment 
• Provide an external focus through appropriate interaction with other departments; seek to understand trends in the CT supply business.

MINIMUM REQUIREMENTS:

B.S. in Scientific, Operations or related field with 7-10 years experience in pharmaceutical drug development with expertise in at least 1 of the following areas: Product Research and Development (PR & D), Manufacturing, Clinical and 5-7 years experience in people management

OR

Advanced degree (e.g., PhD, PharmD, M.S. Management, MBA) with 5-7 years experience in pharmaceutical drug development with expertise in at least 1 of the following areas: Product Research and Development (PR & D), Manufacturing, Clinical and 3-5 years experience in people management

Location:  Indiana – Indianapolis

 5+ to 7 years of experience
Management Experience Required – No
Minimum Education – Bachelor’s Degree

Willingness to Travel – Occasionally

 The Payer Strategy and Marketing Manager is responsible for leveraging extensive managed care payer expertise, strategic thinking and analytical capabilities to identify emerging trends and derive key payer insights that will influence payer customer segment strategies, potential business development deals, and payer marketing capabilities for the Company.  This position will include significant communication and cross-functional collaboration with key stakeholder groups, including the field account organizations, brand payer marketing, contract management & analytics, finance, pricing, and market research teams. This position reports to the Director, Managed Healthcare Services Payer Strategy and Marketing.

KEY OBJECTIVES/DELIVERABLES:

Provide input into the Company’s Managed healthcare Services long-range business plans with focus on further understanding payer customer insights and opportunities/threats in the payer environment. This will include:

Continually monitoring payer and overall environmental trends that could impact the Company’s payer strategies.

 Providing consultation on payer insights and strategy to brand payer teams and other key stakeholders to aid in developing marketing plans and tactics for pre-launch, launch and currently marketed products.

 Collaborating with Government Strategy and Quality team to monitor the political environment and identify strategies and tactics to address/prepare for key governmental changes in the payer environment.

Enhance pricing, reimbursement and access (PRA) capabilities to support potential co-marketing partnerships and B2B launch-related efforts. Also, provide PRA support for due diligence efforts to support potential business development negotiations and evaluations.

 Enhance capabilities to maximize rebate contract performance and brand opportunities through enhanced pull through coordination and improved execution of brand payer strategies with key payer customers.

Based on key payer customer insights, develop, pilot and implement innovative payer marketing programs and capabilities that meet customer needs while also maximizing brand and business opportunities.

 Lead/manage special projects as needed.

MINIMUM REQUIREMENTS:

 Bachelors degree or equivalent

Minimum of 2 years experience with managed markets payer marketing, brand marketing or equivalent health plan/PBM related experience.

 Deep understanding of commercial and public payer customers (e.g. PBMs, MCOs, Employers, Medicaid, Managed Medicaid, Medicare Part D) and the complex dynamics among key players affecting the payer customer

 Qualified candidates must be legally authorized to be employed in the United States. ADDITIONAL SKILLS/PREFERENCES: 

MBA or equivalent experience

 Leadership – ability to lead cross-functional teams

 Strong analytic capabilities and communication skills

 Deep understanding of laws and regulations covering providers and payers

 Ability to apply all Compliance Policies and Procedures (CPP) and Good Promotional Practices (GPP) in unstructured and fluid situations

 Strategic thinking and demonstrated problem solving capability 

Influence (one on one and group setting) – ability to effectively drive decision-making

 Strong history of delivering high quality, sustainable results using skills and capabilities

OTHER CONSIDERATIONS:

10-20% Travel depending on business need

If interested, please submit your resume to resumes@acquis.com.  Thank you!

Location: Indiana 

10+ to 15 years of experience
Management Experience Required – No
Minimum Education – Doctoral

Willingness to Travel – Occasionally

The Data Mining group within Advanced Analytics focuses on developing new models, algorithms, and tools in a wide range of technical and business areas, including many areas of Research & Development, healthcare data from electronic medical records or claims databases, Sales & Marketing, Customer Service/Response, B2B, and more.  This opening is for an experienced researcher in applied mathematics, statistics, informatics or other areas of science with an emphasis on data mining and analysis of data. We are especially interested in persons with expertise in developing models based on findings from data mining efforts and understanding variability and spurious/biased findings (i.e. statistical validity) that may come from data mining projects. Successful candidates are expected to work with multidisciplinary teams to solve challenging problems of importance to drug research, development and commercialization. They will also conduct innovative research, publish and present results in refereed journals and conferences.

The successful candidate will provide statistical/mathematical data mining support in multiple dimensions including:

-                  provides technical leadership and expertise to execute multi-disciplinary or cross functional projects that will influence the Lilly Research Laboratory and the Statistical Science organization;

-                  leads the assessment and introduction of new statistical/mathematical technology and methodology to apply to broader practice;

-                  provides consulting on priority R&D/business projects to define questions/problems of interest, define necessary data sources, and effectively communicate findings to scientific and business partners.

-                  assist with decision-making by effective data mining project plans across Eli Lilly

-                  provide appropriate technical oversight and coaching of a small staff of PhD data mining scientists and statistical programmers.

-                  Work with drug/compound Research Teams and a broad variety of business functions to apply data mining techniques to assist in analysis and decision-making.

-                  Perform research and develop methodologies, especially in data mining and other innovative statistical/mathematical approaches.

-                  Stay current with respect to statistical/mathematical/informatics modeling methodology, to maintain proficiency in applying new and varied methods, and to be competent in justifying methods selected.

-                  Develop approaches or solutions that save time, increase efficiency, facilitate decision-making or otherwise directly impact our drug research or business objectives.

-                  Collaborate with other scientists and drug/compound Team personnel to provide input on study protocol and study design through the use of data mining on past studies or other data sources.

-                  Participate in peer-review work products from other statistical/analytical colleagues, and advise others on technical matters.

-                  Can effectively lead cross-functional or multi-disciplinary groups and use technical expertise to influence business decisions through statistical/mathematical analysis and interpretation.

-                  Collaborate with team/functional colleagues to write reports and communicate results.

-                  Assist with, or be responsible for, communicating study results via manuscripts, or oral presentations in group settings, as well as for communicating one-on-one with key customers and presenting at scientific meetings.

-                  Assist project statisticians in responding to regulatory queries and to interact with regulators as needed.

-                  Have broad understanding about the drug development business to assist in defining data mining projects that may improve efficiency in our business.

-                  Understand disease states in order to enhance the level of customer interaction and collaboration and be seen as a strong scientific contributor.

-                  Perform work in full compliance with assigned curriculum(s) and will be responsible for following applicable corporate, medical, local, and departmental policies, procedures, processes, and training.

-                  Develop, train, educate others in Statistical Sciences and other technical disciplines in research and business on the use of data mining methods and tools.

If interested, please submit your resume to resumes@acquis.com.  Thank you!